1. Gadsby, D.C., P. Vergani, P., and L. Csanády. 2006. The ABC protein turned chloride channel whose failure causes cystic fibrosis. Nature 440:477-483.

2. Csanády, L., Vergani, P., and D.C. Gadsby. 2010. Strict coupling between CFTR's catalytic cycle and gating of its Cl- ion pore revealed by distributions of open channel burst durations. Proc. Natl. Acad. Sci. USA. 107:1241-1246.

3. Csanády, L. and B. Törőcsik. 2009. Four Ca2+ ions activate TRPM2 channels by binding in deep crevices near the pore but intracellularly of the gate. J. Gen. Physiol. 133:189-203.

Further selected publications:

Research Articles

4. Szollosi, A. , Muallem, D.R., Csanády, L., Vergani, P. 2011. Mutant cycles at CFTR's non-canonical ATP-binding site support little interface separation during gating. J. Gen. Physiol. 137:549-62.

5. Tóth B, Csanády, L. 2010. Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel. J. Biol. Chem. 285:30091-102.

6. Szollosi A., Vergani P., Csanády, L. 2010. Involvement of F1296 and N1303 of CFTR in induced-fit conformational change in response to ATP binding at NBD2. J. Gen. Physiol. 136:407-23.

7. Csanády, L. 2009. Application of rate-equilibrium free energy relationship analysis to nonequilibrium ion channel gating mechanisms. J. Gen. Physiol. 134:129-136.

8. Chan, K.W., Wheeler, A., and L. Csanády. 2008. Sulfonylurea Receptors Type 1 and 2A Randomly Assemble to Form Heteromeric KATP Channels of Mixed Subunit Composition. J. Gen. Physiol. 131:43-58.

9. Csanády, L., A.C. Nairn, and D.C. Gadsby. 2006. Thermodynamics of CFTR channel gating: a spreading conformational change initiates an irreversible gating cycle. J. Gen. Physiol. 128:523-533.

10. Csanády, L. 2006. Statistical evaluation of ion-channel gating models based on distributions of LogLikelihood Ratios. Biophys. J. 90:3523-3545.

11. Csanády, L., D. Seto-Young, K.W. Chan, C. Cenciarelli, B.B. Angel, J. Qin, D.T. McLachlin, A.N. Krutchinsky, B.T. Chait, A.C. Nairn, and D.C. Gadsby. 2005. Preferential phosphorylation of R-domain serine 768 dampens activation of CFTR channels by PKA. J. Gen. Physiol. 125:171-186.

12. Csanády, L., K.W. Chan, A.C. Nairn, and D.C. Gadsby. 2005. Functional roles of nonconserved structural segments in CFTR's NH2-terminal Nucleotide Binding Domain. J. Gen. Physiol. 125:43-55.

13. Csanády, L., and V. Adam-Vizi. 2004. Antagonistic regulation of native Ca2+- and ATP-sensitive cation channels in brain capillaries by nucleotides and decavanadate. J. Gen. Physiol. 123:743-757.

14. Csanády, L., and V. Adam-Vizi. 2003. Ca2+- and voltage-dependent gating of Ca2+- and ATP-sensitive cationic channels in brain capillary endothelium. Biophys. J. 85:313-327.

15. Csanády, L. 2000. Rapid kinetic analysis of multichannel records by a simultaneous fit to all dwell-time histograms. Biophys. J. 78:785-799.



16. Csanády, L. 2010. Degenerate ABC composite site is stably glued together by trapped ATP. J. Gen. Physiol. 135:395-398.

17. Csanády, L. 2010. Permeating proton found guilty in compromising TRPM2 channel activity. J. Physiol. 588:1661-1662.

18. Csanády, L. and J.A. Mindell. 2008. The twain shall meet: channels, transporters and things between… Meeting on“Membrane Transport in Flux: the ambiguous interface between channels and pumps” EMBO Rep 9:960-965.


Book Chapters

19. Csanády, L., Vergani, P., Gulyás-Kovács, A., Gadsby, D.C. 2011. Electrophysiological, biochemical, and bioinformatic methods for studying CFTR channel gating and its regulation. Methods Mol Biol. 741:443-69.

Előző oldal: The TRPM2 channel
Következő oldal: Hemosztázis Kutató Részleg